2-Methoxypyrimidin-5-ylboronic acid pinacol ester

2-Methoxypyrimidin-5-ylboronic acid pinacol ester - Names and Identifiers

Name	2-Methoxypyrimidine-5-boronic acid pinacol ester
Synonyms	2-Methoxypyrimidine-5-boronic acid pinacol ester 2-Methoxypyrimidin-5-ylboronic acid pinacol ester 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine Pyrimidine, 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS	1052686-60-8
InChI	InChI=1S/C11H17BN2O3/c1-10(2)11(3,4)17-12(16-10)8-6-13-9(15-5)14-7-8/h6-7H,1-5H3

2-Methoxypyrimidin-5-ylboronic acid pinacol ester - Physico-chemical Properties

Molecular Formula	C11H17BN2O3
Molar Mass	236.08
Density	1.10±0.1 g/cm3(Predicted)
Boling Point	354.3±34.0 °C(Predicted)
pKa	0.94±0.22(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

2-Methoxypyrimidin-5-ylboronic acid pinacol ester - Introduction

2-Methoxypyrimidine-5-boronic acid pinacol ester is an organic compound with the chemical formula C7H11BN2O3. It is a white solid, soluble in organic solvents such as methanol, ethanol and dichloromethane.

2-methoxypyrimidine-5-boronic acid pinacol ester is commonly used as a reagent and intermediate in organic synthesis. It has certain applications in the field of drug synthesis, pesticide synthesis and so on. Since it contains a boronic acid functional group, it can undergo the reaction of boronic acid with other substances, for example with alcohols to form esters.

The preparation method of 2-methoxypyrimidine-5-boronic acid pinacol ester is usually to react 2-methoxypyrimidine with trimethylboronic acid and alcohol to generate the corresponding esterification product. Specific preparation steps and reaction conditions can be adjusted according to specific synthetic schemes.

Regarding safety information, 2-methoxypyrimidine-5-boronic acid pinacol ester has no special hazards during normal use, but the following safety matters still need to be paid attention:
1. avoid contact with skin and eyes, avoid inhaling its dust or steam.
2. Wear protective glasses, gloves and masks during operation.
3. Operate under well-ventilated conditions.
4. need to be sealed when stored, away from the fire and oxidant.
5. Please handle and dispose of waste in accordance with relevant safety regulations.

Last Update：2024-04-09 21:04:16